A UK-based SME offers its capabilities and experience in cell line development to companies, research groups and universities. The SME will work with partners to develop cell lines expressing the recombinant protein of choice in the amounts and quality required for their drug target and drug discovery work. It is envisaged that the partnership will take the form of commercial agreements with technical assistance, manufacturing agreements or technical cooperation agreements. 
A French biotechnology SME is offering an easy and rapid test for evaluation of biocharge level and cleaning efficiency. The test is based on a colorimetric reaction which change the color of the test in presence of viable microorganisms within a few hours. This diagnostic test is used for assessing cleaning efficiency for surfaces (and can be used for liquids). The company is interested in commercial agreement with technical assistance or license agreement.
A Swedish manufacturer of disposable packaging and take-away products is looking for alternative technologies/chemical solutions to replace the use of per- and polyfluoroalkyl substances (PFAS) in their fiber-molded products. A PFAS-free solution should provide barrier properties such as oil-, grease- and water-repellence. The company is looking for solutions that are close to being commercially available and is seeks collaborations with chemical providers under a manufacturing agreement.

The company is seeking collaborations with chemical providers, within a framework of a manufacturing agreement, that can supply the solution to cover both current and future need of moulded fibre based products. Volume is currently around 300 Mpcs and growing with ~30% annually. 

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Artificial tooth germ of human stem cells

In case of a tooth loss, there are several techniques available for artificially replacing the tooth. However, most of these tooth replacement techniques require a severe surgical intervention. Moreover, most of these artificial implants do not fulfill all the physiological requirements a normal tooth should have. Thus there is a need for easily available, physiologically and long lasting transplants.

A Berlin-based German university has developed a method for the ex vivo development of a functional, three dimensional tooth germ. The germ is cultivated from human adult stem cells without using any substrate or growth factors. Cultivation is carried out in culture dishes with a flat bottom and without attaching the cells to the walls of the dish. According to the method stem cells are co-cultured with endothelial cells. Here the ratio between both cell types is important for an optimal formation and an optimal growth of the tooth germ. The tooth germ should be able to induce tooth growth in vitro and in vivo. The development includes an application system for the correct upright positioning of the germ transplant during surgery.
This three-dimensional in vitro organoid can be used as an in vivo transplant or as an in vitro test system.

The university is interested in a cooperation in the framework of a license agreement or a research cooperation agreement. A future licensee would have the authorization to use the technology in return for a fee or a share of royalties. The University is also open to a research cooperation agreement which leads to further development of the technology.

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